Outbreaks from animals in Africa surge by 60% in last decade

Outbreaks from animals in Africa surge by 60% in last decade

WKMG News 6 & ClickOrlando

The number of outbreaks of diseases that jumped from animals to humans in Africa has jumped by more than 60% in the last decade, the World Health Organization said, a worrying sign the planet could face increased animal-borne diseases like monkeypox, Ebola and coronavirus in the future.

There has been a 63% rise in the number of animal diseases breaching the species barrier from 2012 to 2022, as compared to the decade before, the U.N. health agency said in a statement on Thursday.

There was a particular spike from 2019 to 2020, when diseases originating in animals that later infected humans, made up half of all significant public health events in Africa, said WHO. Diseases like Ebola and other hemorrhagic fevers were responsible for 70% of those outbreaks, in addition to illnesses like monkeypox, dengue, anthrax and plague.

“We must act now to contain zoonotic diseases before they can cause widespread infections and stop Africa from becoming a hotspot for emerging infectious diseases,” WHO’s Africa director, Dr. Matshidiso Moeti said in a statement.

While diseases in animals had infected people for centuries in Africa, recent developments like quicker travel across the continent have made it easier for viruses to cross borders, she said.

WHO also noted that Africa has the world’s fastest-growing population, which increases urbanization and reduces roaming areas for wild animals. Scientists also fear that outbreaks that may have once been contained to distant, rural areas can now spread more quickly to Africa’s large cities with international travel links, that might then carry the diseases around the world.

During the West Africa Ebola outbreak that began in 2014, it was not until the disease arrived in capital cities that its spread became explosive, ultimately killing more than 10,000 people and arriving in several cities in Europe and the U.S.

Until May, monkeypox had not been known to cause significant outbreaks beyond central and West Africa, where it has sickened people for decades. According to the U.S. Centers for Disease Control and Prevention, there are now more than 11,000 cases worldwide in 65 countries, the majority of which had not previously reported monkeypox.

WHO announced that it will hold an emergency meeting next week to assess if monkeypox should be declared a global emergency. Last month, the agency said the outbreak did not yet warrant the declaration but said it would review issues such as the possibility that monkeypox might be infecting more vulnerable populations like children, and whether the virus is causing more severe disease.

WHO: COVID-19 cases rise for the 5th week, deaths stable

WHO: COVID-19 cases rise for the 5th week, deaths stable

WKMG News 6 & ClickOrlando

The number of new coronavirus cases reported worldwide rose for the fifth week in a row while the number of deaths remained relatively stable, the World Health Organization reported Thursday.

In the U.N. health agency’s weekly review of the COVID-19 pandemic, WHO said there were 5.7 million new infections confirmed last week, marking a 6% increase. There were 9.800 deaths, roughly similar to the previous week’s figure.

Earlier this week, WHO Director-General Tedros Adhanom Ghebreyesus said the pandemic still qualifies as a global emergency and he was “concerned” about the recent spike.

“The virus is running freely, and countries are not effectively managing the disease burden,” he said during a Tuesday press briefing. “New waves of the virus demonstrate again that COVID-19 is nowhere near over.”

In the last two weeks, cases of COVID-19 reported to WHO surged 30%, driven largely by the hugely infectious omicron relatives, BA.4 and BA.5. The two omicron subvariants have shown a worrisome ability to re-infect people previously vaccinated or who have recovered from COVID.

According to WHO, the biggest increases in COVID-19 cases were seen in the Western Pacific and the Middle East, where they jumped by more than a quarter. Deaths spiked by 78% in the Middle East and by 23% in Southeast Asia, while dropping elsewhere or remaining stable.

WHO said that relaxed COVID-19 surveillance and testing programs in numerous countries have complicated efforts to track the virus and to catch any potentially dangerous new variants.

In the U.S., the new omicron variants have pushed up hospitalizations and deaths in recent weeks, prompting some cities and states to rethink their approaches. White House COVID-19 coordinator Dr. Ashish Jha, during a Wednesday TV appearance, called for booster shots and renewed vigilance against the virus.

The White House response team has also urged all adults 50 and older to urgently get a booster if they haven’t yet this year — and dissuaded people from waiting for the next generation of shots expected in the fall.

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Follow AP’s coverage of the pandemic at https://apnews.com/hub/coronavirus-pandemic

Masks could return to Los Angeles as COVID surges nationwide

Masks could return to Los Angeles as COVID surges nationwide

WKMG News 6 & ClickOrlando

Nick Barragan is used to wearing a mask because his job in the Los Angeles film industry has long required it, so he won’t be fazed if the nation’s most populous county reinstates rules requiring face coverings because of another spike in coronavirus cases across the country.

“I feel fine about it because I’ve worn one pretty much constantly for the last few years. It’s become a habit,” said Barragan, masked up while out running errands Wednesday.

Los Angeles County, home to 10 million residents, is facing a return to a broad indoor mask mandate later this month if current trends in hospital admissions continue, county health Director Barbara Ferrer said this week.

Nationwide, the latest COVID-19 surge is driven by the highly transmissible BA.5 variant, which now accounts for 65% of cases with its cousin BA.4 contributing another 16%. The variants have shown a remarkable ability to get around the protection offered by vaccination.

With the new omicron variants again pushing hospitalizations and deaths higher in recent weeks, states and cities are rethinking their responses and the White House is stepping up efforts to alert the public.

Some experts said the warnings are too little, too late.

“It’s well past the time when the warning could have been put out there,” said Dr. Eric Topol, head of the Scripps Research Translational Institute, who has has called BA.5 “the worst variant yet.”

Global trends for the two mutants have been apparent for weeks, experts said — they quickly out-compete older variants and push cases higher wherever they appear. Yet Americans have tossed off their masks and jumped back into travel and social gatherings. And they have largely ignored booster shots, which protect against COVID-19′s worst outcomes. Courts have blocked federal mask and vaccine mandates, tying the hands of U.S. officials.

“We learn a lot from how the virus is acting elsewhere and we should apply the knowledge here,” said Ali Mokdad, a professor of health metrics sciences at the University of Washington in Seattle.

White House COVID-19 coordinator Dr. Ashish Jha appeared on morning TV on Wednesday urging booster shots and renewed vigilance. Yet Mokdad said federal health officials need to be push harder on masks indoors, early detection and prompt antiviral treatment.

“They are not doing all that they can,” Mokdad said.

The administration’s challenge, in the view of the White House, is not their messaging, but people’s willingness to hear it — due to pandemic fatigue and the politicization of the virus response.

For months, the White House has encouraged Americans to make use of free or cheap at-home rapid tests to detect the virus, as well as the free and effective antiviral treatment Paxlovid that protects against serious illness and death. On Tuesday, the White House response team called on all adults 50 and older to urgently get a booster if they haven’t yet this year — and dissuaded people from waiting for the next generation of shots expected in the fall when they can roll up their sleeves and get some protection now.

Requiring masks again “helps us to reduce risk,” Ferrer told Los Angeles County supervisors. She is expected to discuss details of the potential new county mandate during a public health briefing Thursday afternoon.

“I do recognize that when we return to universal indoor masking to reduce high spread, for many this will feel like a step backwards,” Ferrer said Tuesday.

For most of the pandemic, Los Angeles County has required masks in some indoor spaces, including health care facilities, Metro trains and buses, airports, jails and homeless shelters. The new mandate would expand the requirement to all indoor public spaces, including shared offices, manufacturing facilities, warehouses, retail stores, restaurants and bars, theaters and schools.

It’s unclear what enforcement might look like. Under past mandates, officials favored educating people over issuing citations and fines.

Sharon Fayette ripped off her mask the moment she stepped out of a Lyft ride in Los Angeles Wednesday and groaned when informed another universal mask requirement might be coming. “Oh man, when will it end?” she wondered about the pandemic.

Fayette said she was exhausted by shifting regulations and dubious another mandate would be followed by most residents. “I just think people are over it, over all the rules,” she said.

Barragan said he learned a harsh lesson about the effectiveness of masks when he went without a face covering at a film industry mixer last month in Los Angeles. “I thought it would be fine because we were all outdoors,” said Barragan, 35. A few days later he started feeling sick and, sure enough, tested positive.

He’d avoided catching the virus for more than two years because he was religious about masking up. “The one time I took it off, I caught it!” he laughed.

The nation’s brief lull in COVID deaths has reversed. Last month, daily deaths were falling, though they never matched last year’s low, and deaths are now heading up again.

The seven-day average for daily deaths in the U.S. rose 26% over the past two weeks to 489 on July 12.

The coronavirus is not killing nearly as many as it was last fall and winter, and experts do not expect death to reach those levels again soon. But hundreds of daily deaths for a summertime respiratory illness would normally be jaw-dropping, said Andrew Noymer, a public health professor at the University of California, Irvine. He noted that in Orange County, California, 46 people died of COVID-19 in June.

“That would be all hands on deck,” Noymer said. “People would be like, ‘There’s this crazy new flu that’s killing people in June.’”

Instead, simple, proven precautions are not being taken. Vaccinations, including booster shots for those eligible, lower the risk of hospitalization and death — even against the latest variants. But less than half of all eligible U.S. adults have gotten a single booster shot, and only about 1 in 4 Americans age 50 and older who are eligible for a second booster have received one.

“This has been a botched booster campaign,” Topol said, noting that the Centers for Disease Control and Prevention still uses the term “fully vaccinated” for people with two shots of Moderna or Pfizer. “They haven’t gotten across that two shots is totally inadequate,” he said.

Noymer said if he were in charge of the nation’s COVID response he would level with the American people in an effort to get their attention in this third year of the pandemic. He would tell Americans to take it seriously, mask indoors and “until we get better vaccines, there’s going to be a new normal of a disease that kills over 100,000 Americans a year and impacts life expectancy.”

That message probably wouldn’t fly for political reasons, Noymer acknowledged.

It also might not fly with people who are tired of taking precautions after more than two years of the pandemic. Valerie Walker of New Hope, Pennsylvania, is mindful of the latest surge but is hardly alarmed.

“I was definitely concerned back then,” she said of the pandemic’s early days, with images of body bags on nightly news broadcasts. “Now there’s fatigue, things were getting better and there was a vaccine. So I would say from a scale between one and 10, I’m probably at a four.”

Even with two friends now sick with the virus, and her husband recently recovered, Walker says she has bigger problems.

“Sometimes when I think about it I still put a mask on when I go into a store, but honestly, it is not a daily thought for me,” she said.

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Johnson, AP Medical Writer, reported from Washington state. Associated Press writers Bobby Caina Calvan in New York and Zeke Miller in Washington contributed.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

US regulators OK new COVID-19 shot option from Novavax

US regulators OK new COVID-19 shot option from Novavax

WKMG News 6 & ClickOrlando

The U.S. is getting another COVID-19 vaccine choice as the Food and Drug Administration on Wednesday cleared Novavax shots for adults.

Novavax makes a more traditional type of shot than the three other COVID-19 vaccines available for use in the U.S. — and one that’s already available in Europe and multiple other countries.

Nearly a quarter of American adults still haven’t gotten their primary vaccinations even this late in the pandemic, and experts expect at least some of them to roll up their sleeves for a more conventional option — a protein-based vaccine.

The Maryland company also hopes its shots can become a top booster choice in the U.S. and beyond. Tens of millions of Americans still need boosters that experts call critical for the best possible protection as the coronavirus continues to mutate.

For now, the FDA authorized Novavax’s initial two-dose series for people 18 and older.

“I encourage anyone who is eligible for, but has not yet received, a COVID-19 vaccine to consider doing so,” FDA Commissioner Dr. Robert Califf said in a statement.

Before shots begin, the Centers for Disease Control and Prevention must recommend how they should be used, a decision expected next week.

Novavax CEO Stanley Erck told The Associated Press that he expected the U.S. to expand use of the vaccine beyond unvaccinated adults fairly quickly.

Already the FDA is evaluating it for those as young as 12, Erck said. Novavax also has submitted data on booster doses, including “mix-and-match” use in people who’d earlier received Pfizer or Moderna vaccinations.

The Biden administration has bought 3.2 million Novavax doses so far, and Erck said vaccinations should begin later this month.

Sharon Bentley of Argyle, Texas, is one of the holdouts. Bentley was hesitant about the first COVID-19 vaccines but then her husband volunteered for a Novavax trial, getting two doses and later a booster.

Her husband’s positive experience with a more tried-and-true technology, “that convinced me,” Bentley said, adding that she planned to tell some unvaccinated friends about the option, too.

The Novavax vaccine is made of copies of the spike protein that coats the coronavirus, packaged into nanoparticles that to the immune system resemble a virus. Then an immune-boosting ingredient, or adjuvant, that’s made from the bark of a South American tree is added that acts as a red flag to ensure those particles look suspicious enough to spark a strong immune response.

Protein vaccines have been used for years to prevent hepatitis B, shingles and other diseases. It’s a very different technology than the dominant Pfizer and Moderna COVID-19 vaccines that deliver genetic instructions for the body to produce its own copies of the spike protein. The lesser-used Johnson & Johnson option uses a harmless cold virus to deliver spike-making instructions.

Like the other vaccines used in the U.S., the Novavax shots have proved highly effective at preventing COVID-19’s most severe outcomes. Typical vaccine reactions were mild, including arm pain and fatigue. But FDA did warn about the possibility of a rare risk, heart inflammation, that also has been seen with the Pfizer and Moderna vaccines.

The Novavax vaccine was tested long before the omicron variant struck. But last month, the company released data showing a booster dose promised a strong immune response even against omicron’s newest relatives — preliminary evidence that several of the FDA’s scientific advisers called compelling.

Still, U.S. regulators are planning for a fall booster campaign using Pfizer and Moderna shots that better target omicron subtypes — and Novavax also has begun testing updated shots. Erck said the company could have updated doses available late in the year.

European regulators recently cleared the Novavax vaccine to be used as young as age 12, and several countries have authorized booster doses of its original vaccine.

Earlier manufacturing difficulties held up the vaccine, although Erck said those have been solved and Novavax can meet global demand. Much of the company’s vaccine, including doses for the U.S., are being produced by the Serum Institute of India, the world’s largest vaccine manufacturer.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

Experts rue simple steps not taken before latest COVID surge

Experts rue simple steps not taken before latest COVID surge

WKMG News 6 & ClickOrlando

With new omicron variants again driving hospital admissions and deaths higher in recent weeks, states and cities are rethinking their responses and the White House is stepping up efforts to alert the public.

Some experts said the warnings are too little, too late.

The highly transmissible BA.5 variant now accounts for 65% of cases with its cousin BA.4 contributing another 16%. The variants have shown a remarkable ability to get around the protection offered by infection and vaccination.

“It’s well past the time when the warning could have been put out there,” said Dr. Eric Topol, head of the Scripps Research Translational Institute, who has has called BA.5 “the worst variant yet.”

Global trends for the two mutants have been apparent for weeks, experts said — they quickly out-compete older variants and push cases higher wherever they appear. Yet Americans have tossed off their masks and jumped back into travel and social gatherings. And they have largely ignored booster shots, which protect against COVID-19’s worst outcomes. Courts have blocked federal mask and vaccine mandates, tying the hands of U.S. officials.

“We learn a lot from how the virus is acting elsewhere and we should apply the knowledge here,” said Ali Mokdad, a professor of health metrics sciences at the University of Washington in Seattle.

White House COVID-19 coordinator Dr. Ashish Jha appeared on morning TV on Wednesday urging booster shots and renewed vigilance. Yet Mokdad said federal health officials need to be push harder on masks indoors, early detection and prompt antiviral treatment.

“They are not doing all that they can,” Mokdad said.

The administration’s challenge, in the view of the White House, is not their messaging, but people’s willingness to hear it — due to pandemic fatigue and the politicization of the virus response.

For months, the White House has encouraged Americans to make use of free or cheap at-home rapid tests to detect the virus, as well as the no-cost and highly-effective antiviral treatment Paxlovid that protects against serious illness and death. On Tuesday, the White House response team called on all adults 50 and older to urgently get a booster if they haven’t yet this year — and dissuaded people from waiting for the next generation of shots expected in the fall when they can roll up their sleeves and get some protection now.

Los Angeles County, the nation’s largest by population, is facing a return to a broad indoor mask mandate if current trends in hospital admissions continue, health director Barbara Ferrer told county supervisors Tuesday.

“I do recognize that when we return to universal indoor masking to reduce high spread, for many this will feel like a step backwards,” Ferrer said. But she stressed that requiring masks “helps us to reduce risk.”

LA County has long required masks in some indoor spaces, including health care facilities, Metro trains and buses, airports, jails and homeless shelters. A universal mandate would expand the requirement to all indoor public spaces, including shared offices, manufacturing facilities, warehouses, retail stores, restaurants and bars, theaters and schools.

The nation’s brief lull in COVID deaths has reversed. Last month, daily deaths were falling, though they never matched last year’s low, and deaths are now heading up again.

The seven-day average for daily deaths in the U.S. rose 26% over the past two weeks to 489 on July 12.

The coronavirus is not killing nearly as many as it was last fall and winter, and experts do not expect death to reach those levels again soon. But hundreds of daily deaths for a summertime respiratory illness would normally be jaw-dropping, said Andrew Noymer, a public health professor at the University of California, Irvine. He noted that in Orange County, California, 46 people died of COVID-19 in June.

“That would be all hands on deck,” Noymer said. “People would be like, ‘There’s this crazy new flu that’s killing people in June.’”

Instead, simple, proven precautions are not being taken. Vaccinations, including booster shots for those eligible, lower the risk of hospitalization and death — even against the latest variants. But less than half of all eligible U.S. adults have gotten a single booster shot, and only about 1 in 4 Americans age 50 and older who are eligible for a second booster have received one.

“This has been a botched booster campaign,” Topol said, noting that the Centers for Disease Control and Prevention still uses the term “fully vaccinated” for people with two shots of Moderna or Pfizer. “They haven’t gotten across that two shots is totally inadequate,” he said.

Noymer said if he were in charge of the nation’s COVID response he would level with the American people in an effort to get their attention in this third year of the pandemic. He would tell Americans to take it seriously, mask indoors and “until we get better vaccines, there’s going to be a new normal of a disease that kills over 100,000 Americans a year and impacts life expectancy.”

That message probably wouldn’t fly for political reasons, Noymer acknowledged.

It also might not fly with people who are tired of taking precautions after more than two years of the pandemic. Valerie Walker of New Hope, Pennsylvania, is mindful of the latest surge but is hardly alarmed.

“I was definitely concerned back then,” she said of the pandemic’s early days, with images of body bags on nightly news broadcasts. “Now there’s fatigue, things were getting better and there was a vaccine. So I would say from a scale between one and 10, I’m probably at a four.”

Even with two friends now sick with the virus, and her husband recently recovered, Walker says she has bigger problems.

“Sometimes when I think about it I still put a mask on when I go into a store, but honestly, it is not a daily thought for me,” she said.

___

Associated Press writers Christopher Weber in Los Angeles, Bobby Caina Calvan in New York and Zeke Miller in Washington contributed.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.